Just my opinion here, but I think that a good chunk of this issue may be that you are trying to calibrate to an RH other than 75%. Hygrometers like the Hygroset II are designed to calibrate to 75%, not 65, 67 or some other number. In my experience, the Hygroset II is one of the most accurate hygrometers that I have owned but is also among the most difficult to calibrate.
To calibrate them properly it usually takes me a couple of days. Generally what I do is the following:
1) I let them sit in the sealed environment for 24 hours with either a Boveda calibration kit or table salt in solution (both work equally well)
2) depending on how far they are away from 75%, I will adjust the knob the appropriate amount of clicks either up or down.
3) when I hit the recalibrate button it is designed to set them at 75, not any other number.
4) because I want them to be completely accurate, I will then put them back in the sealed environment and let them sit for another 24 hours
5) if they still read 75% after 24 hours they are good to go. If they are off by a point or 2 I will adjust the knob appropriately, hit recalibrate and then put them back in for another 24.
6) repeat step 5 as necessary.
This definitely takes a little bit of patience but is worth it to me since I have had some issues with other brands (specifically Xikar) in the past. The key here is that digital hygrometers like the Xikar and Hygroset II are designed to recalibrate to 75%. When you hit the recalibrate button on them, 75% is the number that they are supposed to go to, not something else.
Edit: Once again my opinion here....I may be way off base but I think that the reason you are getting readings from the 50's to the 80's is as follows:
Low reading: When you open up the sealed environment the ambient air in your room rushes into your container which is why you are getting a low reading in the 50's. I live in MN so I am painfully aware of what the humidity is in our houses this time of year. The reason that you need to let them sit in a sealed environment for 24 hours is so the Boveda pack or salt solution can effectively fill your sealed space with a 75% environment.
High reading: if you are trying to calibrate your hygrometer using a 65% Boveda pack, here is what probably happened. The environment you created was 65% but your hygrometer is designed to recalibrate to 75% so when you hit the recalibrate button you have now created a reading that is off by 10 points (65% is now reading as 75%). If you now put this mis-calibrated hygrometer into an environment that is 70% or 75% it is going to read 80% or 85% (10 points higher).