It seems the real deep secrets of good cigar tobacco lie within the way it been fermented.
"Aging tobacco is a catabolic process where enzymes break down polysaccharides (cellulose) into monosaccharides (glucose). It's how harshness and "off" or grassy flavours are mitigated. This process can be accelerated by adding cellulase, amylase and other enzymes to tobacco leaf and then raising the temperature to 50 degrees C for several days to allow the enzymes break down the leaf into simpler carbohydrates. The process is similar to composting. It makes harsh, immature tobacco into a smooth and smoke-able product."
(This is a quote from a guy named Dougger who apparently had some success with this method on a small scale basis using LO leaf but has since disappeared.)
Be that as it may, it seems that this is a doable project that could possibly render a more sociable tobacco.
It would seem reasonable that adding enzymes would accelerate the digestive process thus helping farmers get the product out to market faster. I have also seen companies that offer 'tobacco enzymes' for sale for commercial use. So there is proof that it exists and is being used as an active ingredient in fermentation. I've found little information on this topic on the specifics.
Myself and a few others here have tried a few simple experiments using enzymes with little to no success. Looking back I'd be the first to admit I made errors along the way and lacked important guide lines and equipment set-up that ultimately caused the failure. Shooting in the dark. Things need to be pretty specific for mother nature to perform the magic.
Things like uniform and constant temperature control are extremely important. If temps get too high, even slightly, it destroys the enzymes. Humidity control is another biggie, Too wet and mold will quickly destroy your tobacco. Too dry and it won't activate the enzyme activity. Tricky stuff.