It definitely helps to have a flight stick for the flying aspect. I was using a mouse at first, but broke down and actually dug out my flight stick from 2005 and it is the "bomb". I am still amazed at how many people are so proficient at killing me in so many ways though, I guess I just need to level up a lot more for better weapons.
As for fast reflex games, that seems more my style. I loved Quake 3 Rocket Arena back in 2000'ish and that game was all fast twitch response. You just have to get used to not panicing and slow down your response to gradually learn to play to that speed. After a while it actually becomes natural.