I've only smoked one, but it was very different from the Opus. While I'm generally skeptical of the whole "most of the flavor comes from the wrapper" line, the wrapper on this one does seem to add a lot of flavor and set it apart, flavor-wise, from the Opus.I've not had an Anejo yet myself, and just had my first Opus (loved it!). I know that they have the same exact filler--the Anejo is basically an Opus Maduro.
-Charles